Few Words about Walter Pierpaoli, M.D.
He is one of the great avant-garde professional researchers and physicians today who are searching for the central cure for aging disorders.
He describes himself thus
“I am not a wizard or a sorcerer but simply a man curious of nature and biology who has spent almost 40 well documented years in the merry companionship of mice, waiting for them to teach me how and why we age and die. My main feature is endurance and a deeply rooted ability to escape from the fashion of science. I have definitely interpreted the biological expression of the genetic programme of aging in the “pineal network,” and am now trying to stop and also reverse aging. My solitary path has not yet been followed, but the crowd generates aggressivity and confusion because many motivations in health care are not addressed to disease prevention but, on the contrary, to there maintenance. The “ultimate defiance” has started and the answer can only be through strict scientific documentation. Mice live two to three years, humans sometimes 100 and over. Some may care to wait to see, but in the meantime I protect my pineal gland from aging by using melatonin.”
Why Does Melatonin Prolong Your Life?
Melatonin prevents aging-related diseases, delays your aging, and automatically prolongs your life by simply impeding and postponing the progressive central, hypothalamic alteration of feedback hormonal regulation, as described beautifully by Dilman (12). It does so not directly, but rather smartly by maintaining youthful pineal function! In fact, obviously night administration of melatonin prevents the aging pineal gland from producing it. This regular night order “do not work”to the pineal, not only protects the “central hormonal director”, but even induces a recovery of its regulatory capacity to modulate hormonal cyclicity, to the extent that the pineal gland recovers its juvenility. This is most significantly demonstrated by my experiments in which a young pineal gland grafted into a much older recipient induces a very significant life prolongation. Being the grafted pineal unable to produce itself melatonin because it is dissected from its neural connections, obviously the central “life clock” is located in the pineal itself but its mechanisms do not depend on melatonin! The aging pineal in fact loses its ability to produce a night peak of melatonin, being this a clear signal of its own aging. Therefore we have now shown beyond any doubt that exogenous melatonin, by protecting pineal aging through its positive feedback on the pineal itself, simply maintains the capacity of the young pineal to control cyclic release of all hormones, and it does this by maintaining and preventing pineal aging (8,9,13). Not only yhe pineal is our central “life clock”, it also actively induces our aging in the course of its life, aging and death “program” (14). Clearly genetically and evolutionary originated mechanisms in the pineal gland modulate the course of our life and also generate the signals at the end of our life program. This is shown in the experiments we reported in a recent work (15). Therefore the basic mechanisms for our aging must be sought in our pineal gland and in its links to the entire neuroendocrine network (16). We age because our “pineal network” is “programmed” to deteriorate (12) and therefore we must use exogenous night melatonin in order to maintain its integrity and thus prevent the typical course of the aging syndrome inside the pineal gland. Only natural melatonin can protect the pineal gland from programmed aging!
Emmy’s Story
My mother-in-law Emmy Hugly, living in Horw near Lucerne in Switzerland, is now 94 year-old, perfectly healthy and Parkinson-free in the last 15 years, with no intention to give up! Her story is narrated shortly in the “Melatonin Miracle” (1) and also in my recent book published in Italy “120 and longer, average” (2). She runs shopping every day, and when we celebrate her birthdays, she loves dancing and playing the piano. I am used to visit her from time to time and make a record of her health and behavior with a video-camera. She would love to see visitors and journalists coming to her home. They will be enthusiastically received! She will prepare for them excellent tea and serve with no shaking hands, as was the case 20 years ago, when she had severe and rapidly worsening Parkinson. Emmy is undoubtedly the longest melatonin-taking person in the world. She started in the early 80th of the last century, when I told her of my experiments with aging mice and how the administration of nocturnal melatonin in the drinking water was producing a remarkable rejuvenation, resulting in a delayed aging or/and consequent life prolongation. She asked me to give her the “pills” and she religiously followed my prescription. Twenty years ago I prepared for her in my lab 3mg melatonin capsules. Of course, she is now taking magic Melatonin Pierpaoli with zinc and selenium, as a kind an “evening rhythus” every night. The embittered adversaries of innocent melatonin should visit her before their life program has expired! Of course the lesson we can learn from Emmy is what I was repeating in my “shout in the desert” Conferences (3-5): reversal of aging we can observe in 2-3-year living mice, but in order to see what happens in humans we just must wait! Lucky her, Emmy did not want to wait for a permit of the “Regulatory Bodies” in Switzerland to start taking melatonin; she wanted to live longer and Parkinson-free! According to the basic principles described by the great American anthropologist Ashley Montagu in his famous book “Growing Young” (6), Emmy is the living emblematic example of a neotenic (maintaining youth) person, born young and staying young until death, opposite to the typical necrophilic personality of the depressed and negative person born old and permanently old and aging until the “liberation” of death. Of course now many follow Emmy’s virtuous path, regaining vitality every day, month and year.
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Every instant of our daily life is completely imprinted by solar and lunar ciclicity, from fertilization of the egg until the last breath of life. Being life on our planet shaped and inextricably associated with planetary and solar cyclicity, it is no wonder that its progressive deterioration, which is clearly represented by our growth, maturity, fertility and finally aging and death, is governed by extremely strong and genetically determined rules.This aspect is amply represented by the demonstration that the hormones which regulate fertility and reproduction, are the same also controlling immunity (see Figure 1). But the dominance of the system gives priority to fertility and reproduction, in so far Nature has thus allowed a species to survive (7). Apparently the logic inevitability of this fact encounters the illogic opposition of many doctors and scientists! It is a riddle to me, not my demonstration of a central life and death clock in the pineal, but the absence of any experiment from those who criticize my work! It is in fact known that any kind of criticism bears no fundament unless it is founded on the repetition of a “doubtful” scientific work with the identical methods, and on its publication in a reviewed journal. Did anybody replicate my experiments with melatonin and pineal grafting (8,9)? I do believe no! This is a true mystery of the 20th century. This question must be addressed in particular to those scientists who, without any justification whatsoever, spreaded injury and false news by hiding behind the sheltering curtain of “prestigious journals” (10,11). Their behavior must be condemned and made public because their irresponsible and irrational attacks have produced an awful damage to millions of persons around the world.
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Original Article source: http://www.drpierpaoli.com/ENG/Melatonin-Prolongs-Your-Life
About Dimitri Detchev
Energy Healer - Following practices and Theories to all aspects of the Universal Energy - Prana - Bio-field.